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The formal study of semantics intersects with many other fields of inquiry, including lexicology, syntax, pragmatics, etymology and others. Independently, semantics is also a well-defined field in its own right, often with synthetic properties. In the philosophy of language, semantics and reference are closely connected. Further related fields include philology, communication, and semiotics. The formal study of semantics can therefore be manifold and complex.

Semantics contrasts with syntax, the study of the combinatorics of units of a language (without reference to their meaning), and pragmatics, the study of the relationships between the symbols of a language, their meaning, and the users of the language. Semantics as a field of study also has significant ties to various representational theories of meaning including truth theories of meaning, coherence theories of meaning, and correspondence theories of meaning. Each of these is related to the general philosophical study of reality and the representation of meaning.